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Avanafil is an active pharmaceutical ingredient (API) used in the treatment of erectile dysfunction (ED) in men. It is marketed under the brand name Stendra in some countries. Avanafil belongs to the class of medications known as phosphodiesterase type 5 (PDE5) inhibitors, which also includes sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra).
Similar to other PDE5 inhibitors, avanafil works by increasing blood flow to the penis during sexual stimulation, facilitating the achievement and maintenance of an erection. It specifically targets the enzyme PDE5, which degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. By inhibiting PDE5, avanafil allows cGMP levels to increase, promoting smooth muscle relaxation and improved blood flow to the penile area.
Avanafil is known for its rapid onset of action, typically taking effect within 15 to 30 minutes after ingestion. It may start working faster compared to other PDE5 inhibitors. The duration of action of avanafil is usually around 4 to 6 hours, during which sexual stimulation can lead to an erection.
As with any medication, avanafil may cause side effects, including headache, flushing, nasal congestion, back pain, and muscle aches. It is important to follow the prescribed dosage and instructions provided by your healthcare professional and consult with them for personalized advice and guidance.
When taking avanafil (brand name Stendra), it is important to follow the instructions provided by your healthcare professional. Here are some general guidelines for taking avanafil:
- 1.Dosage: Take avanafil exactly as prescribed by your healthcare provider. The typical recommended starting dose is 100 mg, taken orally as needed, approximately 15 to 30 minutes before sexual activity. However, your healthcare provider may adjust the dosage based on your individual needs and response.
- 2.Timing: Avanafil should be taken before sexual activity, as it works in response to sexual stimulation. It is not intended for daily use or as a cure for erectile dysfunction.
- 3.Food Intake: Avanafil can be taken with or without food. However, taking it with a high-fat meal may delay its onset of action, so it is generally recommended to take it on an empty stomach for faster results.
- 4.Avoid Alcohol and Grapefruit Juice: Consumption of alcohol and grapefruit juice may increase the risk of side effects or reduce the effectiveness of avanafil. It's advisable to avoid these substances while taking the medication.
- 5.Follow Medical Advice: Always consult your healthcare provider for personalized advice regarding avanafil. They can provide specific instructions based on your medical history, other medications you may be taking, and any underlying health conditions.
- 6.Do Not Exceed the Recommended Dose: It is important to stick to the prescribed dosage and not exceed the recommended amount. Taking more avanafil than prescribed does not enhance its effectiveness and may increase the risk of side effects.
Remember, avanafil is a prescription medication, and it should only be used under the guidance of a healthcare professional. If you have any questions or concerns about how to take avanafil, consult with your healthcare provider for appropriate guidance.
Avanafil (brand name Stendra) may cause side effects in some individuals. While not everyone will experience side effects, it's important to be aware of the potential risks. Common side effects of avanafil include:
- 2.Flushing (redness or warmth in the face, neck, or chest)
- 3.Nasal congestion
- 4.Back pain
- 5.Muscle aches
- 6.Stomach upset or indigestion
These side effects are usually mild and temporary, resolving on their own without medical intervention.
In some cases, avanafil can cause more serious side effects that require immediate medical attention. These less common but potentially serious side effects may include:
- 1.Sudden vision loss or changes in vision
- 2.Sudden hearing loss or changes in hearing
- 3.Irregular heartbeat or chest pain
- 4.Shortness of breath
- 5.Dizziness or fainting
- 6.Prolonged or painful erection lasting more than 4 hours (priapism)
If you experience any of these serious side effects, seek medical attention promptly.
It is important to note that this list is not exhaustive, and there may be other side effects associated with avanafil. Additionally, individual reactions to the medication can vary. If you have any concerns or questions about avanafil's side effects or its suitability for you, it's best to consult with your healthcare provider for personalized advice. They can provide you with more specific information based on your medical history and circumstances.