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Dapoxetine belongs to the serotonin reuptake inhibitors or SSRIs. It regulates the amount of serotonin in the brain. This body’s own substance plays a role in emotions and moods. Doctors prescribe it for the sexual disorder of premature ejaculation.
Dapoxetine has been on the international market since 2010. It is available by prescription in tablets under the brand name Priligy.
Check the pharmacy label for the correct dosage. When? Take the tablet 1 to 3 hours before with half a glass of water. Do not take more than 1 dose per day. Only use this medicine occasionally, not daily.
How long? This medication is usually prescribed for a maximum of six months. After you have used it about 6 times, or after a month, your doctor will discuss the effects and side effects with you.
In addition to the desired effect, this drug can sometimes cause side effects. The main side effects are the following.
- Nausea. You will be less affected by this if you take the tablet with some food.
- Dizziness or (rarely) fainting when you stand up or sit up, the first hours after taking it. Get up slowly if you experience this. Therefore, try this medicine first. Do you suffer from it quickly? Then make sure you drink enough. For example, by taking this medicine with a full glass of water.
- Less desire to make love, difficult erection.
- Diarrhea or other gastrointestinal complaints, such as constipation, vomiting, abdominal pain, flatulence, and heartburn. Have you ever had a stomach or intestinal ulcer or other serious stomach or intestinal diseases, such as stomach or intestinal bleeding? You are then more likely to have side effects on the stomach and intestines. Consult with your doctor. In addition to this medication, your doctor may also prescribe a stomach protective medication.
- Dry mouth. Frequent use of this medication may make your teeth more likely to develop cavities. Therefore, brush and floss extra well if you notice that you suffer from a dry mouth. If necessary, have the dentist check more often.
- Insomnia, anxiety, agitation, restless feeling. Very rarely nightmares and teeth grinding.
- Drowsiness, fatigue, drowsiness, yawning, and reduced ability to concentrate. This is especially troublesome with activities that require your attention, such as driving, climbing a ladder, or monitoring a process at work. Do you suffer from these side effects? Do not undertake risky activities.
- Trembling, sweating, or flushing.
- Blurred vision or ringing in the ears. Very rarely eye pain or spinning sensation. Consult your doctor if this continues to bother you.
- Tingling or numbness in hands or feet. Very rarely itch.
- Increase in blood pressure for several hours after ingestion
- Taste disorders.
- Heart complaints, such as palpitations, accelerated heartbeat, or, conversely, a slowed heartbeat. Talk to your doctor if you suffer from this.
- Depressive thoughts or other mood changes such as indifference. Contact your doctor if you notice that you are getting depressed.
- Confusion, not being able to think clearly.
- If you have diabetes mellitus: Your blood glucose may change because of this medicine. Therefore, check your blood glucose more often.
- People with epilepsy are at risk of having a seizure. Discuss this with your doctor.
Consult your doctor if any of the above side effects are too much for you or if you experience any other side effects that concern you.
Regular: affects more than 30 out of 100 people Uncommon: affects 10 to 30 out of 100 people Rare: affects 1 to 10 out of 100 people Very rare: affects less than 1 out of 100 people
This drug interacts with other medications. The text below only lists the active substances of these medicines, not the brand names. You can check whether your medicine contains one of these active substances in your package leaflet under the heading ‘composition’.
The drugs with which the main interactions occur are as follows.
- Other drugs that reduce responsiveness. These medicines often have a yellow warning sticker on the packaging. The effects on, for example, reaction capacity and coordination capacity reinforce each other. Do not drive if you are taking another drug that affects reaction time in addition to dapoxetine.
- Anti-inflammatory pain relievers, such as ibuprofen, diclofenac, acetylsalicylic acid, naproxen, and celecoxib. These medications can cause side effects on the stomach, such as stomach bleeding. If you take dapoxetine on the same day, you are more likely to experience these side effects. Therefore, on the days when you want to use dapoxetine, use paracetamol as a painkiller. It doesn’t have that drawback. Be extra vigilant if you do need to take dapoxetine together with an anti-inflammatory painkiller, and consult your doctor if you have an upset stomach. Usually, the doctor advises you to take a stomach protector to prevent stomach complaints. Consult with your doctor if this is necessary for you.
- The anticoagulant drugs acenocoumarol and phenprocoumon. Do not take dapoxetine if you are taking any of these anticoagulant medications. Dapoxetine can enhance the effect of the blood thinner.
- The water tablets chlorthalidone, chlorothiazide, hydrochlorothiazide, epitizide and indapamide. If you take one of these drugs and dapoxetine several times a week, you are at risk of a sodium deficiency in the blood. This can mainly be caused by fluid loss, such as vomiting, diarrhea, fever, and heat. You will notice this from sudden severe fatigue, drowsiness, difficulty speaking, decreased appetite, vomiting, and diarrhea. Then notify your doctor immediately.
- The anti-nausea drug metoclopramide. The side effects of metoclopramide may increase. You may experience stiff muscles, trembling, difficulty walking or talking restlessness, and sudden muscle twitching. Consult with your doctor.
When combined with the following medicines, there is a risk of a serious side effect, serotonin syndrome (this can be noticed by trembling, trembling, urge to move, muscle twitching, agitation, confusion, anxiety, fever, sweating, increased heart rate, and drowsiness). Do not use dapoxetine if you take one of the following medications. Consult with your doctor.
- The painkillers fentanyl, oxycodone, pethidine, and tramadol ;
- The antibiotic linezolid ;
- Selegiline and rasagiline, are medicines for Parkinson’s disease;
- Phenelzine, tranylcypromine, and moclobemide, are medicines for depression.
- The following warning also applies to the medicines selegiline, rasagiline, phenelzine, tranylcypromine, and moclobemide: do you have to start with one of the medicines, and have you used dapoxetine? It will take a week before you can safely use these medicines. Conversely, it takes 2 weeks before you can start using dapoxetine after stopping these medicines. With moclobemide, you can start using dapoxetine as early as 1 day after stopping.
Not sure if any of the trade-offs above are of interest to you? Please contact your pharmacist or doctor.
driving? This medication can cause side effects such as drowsiness, loss of concentration, drowsiness, and dizziness. Do not participate in traffic if you suffer from these side effects. These side effects usually pass within a few hours.
drinking alcohol? Alcohol enhances the sedative effect of this drug. As a result, alcohol can make you very drowsy. Therefore limit the use of alcohol and prefer not to drink it.
eat everything? There are no restrictions on this with this drug.
using party drugs? Do not use drugs or party drugs while taking this medication. For example, no ecstasy or LSD. The combination can cause serious side effects.
Have you been taking this medication daily or several times a week for several weeks? There is a small risk of withdrawal symptoms if you stop. You may have trouble sleeping or feel dizzy after you stop taking this medicine, even if you don’t take it every day.