Buy Tadalafil Online

Tadalafil is the generic version of the erectile dysfunction drug Cialis, the branded drug which is made by Lilly. It is available as both a daily or on demand pill.
Tadalafil (also known as ‘generic Cialis’) is a tablet for erectile dysfunction. It is the non-branded version of a well-known drug used to treat male impotence. The branded treatment is manufactured and marketed by Lilly, however the patent on this medicine expired in 2017. Consequently, other manufacturers are now legally able to produce Tadalafil for the purpose of erectile dysfunction.
You can buy Tadalafil online from our UK pharmacy. Like the branded version, it is available as a daily pill (Tadalafil 2.5mg and Tadalafil 5mg) and as an ‘on-demand’ or ‘weekend’ pill (Tadalafil 10mg and Tadalafil 20mg).

What is ED?

Erectile dysfunction is a condition which is perhaps more common than many suspect. Also known as impotence, it is characterised by an inability to achieve an erection during sexual intercourse, or maintain one long enough to have penetrative sex. It is thought that around half of men over the age of 40 will encounter the condition at some point, although men of any sexually-active age can experience ED.
There are a number of reasons why men experience the condition. Sometimes these might be psychological in nature: often men who are in a new relationship will, for instance, be eager to impress their new partner. This can lead to a high pressure situation, where nervousness can impede erectile function. This is commonly referred to as ‘performance anxiety’. At other times, a man might be distracted by other issues in their life, such as a burgeoning workload in their professional life. This might also affect their performance during sex, and induce erectile problems.
It’s also very common for erectile dysfunction to be self-perpetuating. The worry of not being able to get an erection might make it harder to achieve one, creating something of a cycle.
In other cases, erectile problems may come about as a result of physical issues. These are often rooted in poor blood flow, which is why ED is so often (albeit not exclusively) a problem for older men. As men approach middle age, the risk of high blood pressure and other conditions inhibiting circulation increases, which can lead to erectile dysfunction.
Lifestyle factors can also contribute to impotence. Men who smoke, drink alcohol to excess, keep a poor diet or don’t exercise enough may typically be more susceptible to developing erectile dysfunction due to physical factors, than those men who maintain a healthy routine (by not smoking, limiting alcohol consumption, eating healthily and exercising regularly).
Many men are able to tackle the condition by making positive improvements to their lifestyle. Men who have psychologically-induced ED may also benefit from speaking to their partner about the issue, or by directly addressing the problem responsible (such as a professional workload) for causing them anxiety and stress.
For men who have ED due to physical reasons, treatment can help if their symptoms have not responded to changes in lifestyle.

'Generic' Cialis

Tadalafil is the generic edition of the branded version of this drug which has been available since 2003, and is one of the leading medications in the world for ED. In 2017, the patent on the drug expired, making generic Cialis legally available in the UK.
You should still exercise caution whenever buying generic Cialis or Tadalafil online. Make sure you use a GPhC-registered pharmacy, and read our information on buying ED medicine online safely.

How does Tadalafil work?

Tadalafil is a PDE5 inhibitor, which works by increasing blood flow to the penis. You can read up on the different types of ED treatment available on our dedicated treatment page.
PDE5 is an enzyme which is naturally present in the body and helps to regulate the flow of blood. In men with ED, this enzyme has a restrictive effect on blood vessels, which means that blood is not as able to enter the shaft in the penis (corpus cavernosum), a process necessary for an erection to occur.
Tadalafil reduces the effects of this enzyme, which allows blood to travel to and enter the penis more ably. This allows the user to achieve and sustain an erection suitable for penetrative sex.
Please note that Tadalafil is not an aphrodisiac. You will need to be sexually stimulated in order for it to work.

What do the different Tadalafil doses do?

There are two forms of Tadalafil available. The daily form is taken every day, and is essentially ‘effective’ all of the time. The weekend form is taken on demand, and the effects can last for up to 36 hours.

Choosing Tadalafil daily 2.5mg and 5mg

This option suits men who are happy to take one tablet at the same time each day. It allows for more spontaneity as the low dose offers continuous treatment, therefore sex can be enjoyed without having to plan when to take medication. If the 2.5mg tablet does not provide sufficient results, then your doctor has the option to increase to 5mg.

Choosing Tadalafil ‘weekend’ 10mg and 20mg

The term ‘weekend pill’ refers to the fact that these doses can be effective for up to 36 hours. The term ‘effective’ does not mean a constant erection. This means that the drug will help to produce an erection when sexually stimulated during the ‘effective’ time period. If you develop an erection which does not go away or lasts for more than four hours continuously, seek medical attention right away.
The 10mg is usually the starting dose and is taken around 30 minutes prior to having sex. The 20mg dose is also taken 30 minutes before sex and can be prescribed when the lower dose has not produced completely satisfactory results.

Can I get Tadalafil online?

You can now purchase Tadalafil online from our UK pharmacy. All orders are reviewed by a practising doctor or pharmacy prescriber prior to issue. Once approved, your order will be dispensed and then shipped to you by 24-hour tracked courier. In most cases, your parcel will arrive within one working day.


Before taking this treatment, make sure you read the instructions in the patient information leaflet provided. You should only ever use the medication as directed by your prescriber. If you are unsure of anything, ask your doctor or pharmacist for further advice.

Tadalafil 10mg and Tadalafil 20mg (on demand)

  • Swallow one tablet whole with a glass of water 30 minutes before you plan to have sex.
  • The effect of the tablet can last for up to 36 hours.
  • It should not be taken more than once a day and is not suitable for continuous daily use.

Tadalafil Daily 2.5mg and Tadalafil Daily 5mg

  • Take one tablet a day, at approximately the same time each day.
  • Swallow whole with water.
  • The daily form may be beneficial to men who plan to have sex two or more times a week.
  • If you miss a dose, take it when you remember, but do not double up on doses to make up for a missed one. If your next dose is almost due, simply skip the one you have missed and carry on taking the treatment as normal.

The below applies to all doses of Tadalafil

  • Tadalafil increases blood flow to the penis. It will therefore not provide sexual stimulation and work on its own. You will still need to be sexually stimulated for it to work.
  • The effectiveness of Tadalafil may be lessened if taken following a large meal or while drinking alcohol. Grapefruit juice can also cause interactions, and should be avoided if you are using Tadalafil.
  • It is advised to limit your alcohol consumption if you have erectile dysfunction. Drinking alcohol can, for a short time, lower blood pressure, and increase the risk of ‘postural hypotension’ (dizziness when standing up) in men taking Tadalafil.
  • Never exceed the dose recommended by your prescriber.
  • If you develop side effects, or if the dose you are taking is not effective, speak to your doctor.
  • During consultation, your doctor needs to be told about any pre-existing medical conditions or other treatments you are using.
  • Never take recreational drugs if you are also taking erectile dysfunction medication.
The above is only a brief summary of the directions you will need to follow when using Tadalafil. Refer to the patient information leaflet for more detailed instructions.

Side effects

Not everyone who uses Tadalafil will develop side effects, but it is important that you are aware of the side effects associated with it. See a doctor immediately if you notice any signs of:
  • an allergic reaction (hives, swelling of the face, lips or throat, or difficulty breathing)
  • chest pain
  • priapism (an erection lasting for more than four hours and does not go away)
  • sudden sight or hearing loss
  • or any other side effects that become serious.

Common (1 in 10 people or less):

Headache, back and muscle pain, flushing and redness, stuffy nose and indigestion.

Uncommon (1 in 100 people or less):

Feeling dizzy, stomach discomfort, nausea and vomiting, reflux, blurred vision, eye pain, breathing difficulty, blood in the urine, prolonged erections, palpitations, change in heart rate, hypertension, hypotension, tinnitus, swelling of the hands, feet or ankles, tiredness.

Rare (1 in 1000 people):

Fainting, seizures and temporary memory loss, swelling eyelids, redness in the eyes, sudden hearing loss, hives, penile bleeding or blood in the semen, and increased perspiration, heart attack or stroke.
The above is only a summary. Please refer to the leaflet provided for more detailed information.


Taking it with other medications

Tell your prescriber about any other treatments you are using when undergoing consultation for Tadalafil.
You must not take Tadalafil if you are on nitrate medication.
During consultation, it is particularly important to make your doctor aware if you are taking any of the following, as they may interact with Tadalafil: alpha blockers or any other high blood pressure treatment; riociguat; medicines for benign prostatic hyperplasia called ‘5-alpha reductase inhibitors’; antifungal medicines such as ketoconazole; protease inhibitors for HIV or AIDS; phenobarbital, phenytoin or carbamazepine (anticonvulsants); rifampicin, erythromycin, clarithromycin or itraconazole (used in infections); or other impotence treatments.

Conditions to look out for

Tell your doctor about any medical problems you have or have had in the past during consultation.
You must not take Tadalafil if you: are allergic to any ingredients in it; have had a heart attack in the previous 90 days, or have serious heart disease; have had a stroke in the last six months; have low blood pressure or high blood pressure which is not being controlled; have ever had sight loss due to ‘stroke of the eye’ (non-arteritic anterior ischemic optic neuropathy, or NAION).
It is very important to let your doctor know if you have: a heart condition; sickle cell anaemia; multiple myeloma; leukemia; any deformity of the penis; an erection lasting for longer than four hours; or a serious liver or kidney problem.

Alcohol and grapefruit juice

Men who have erectile dysfunction should note that excessive alcohol consumption can worsen symptoms. Drinking alcohol and taking Tadalafil at the same time can increase the risk of dizziness when standing up.
Grapefruit juice can also interfere with the function of Tadalafil. It is better to avoid drinking grapefruit juice when using this treatment.

Recreational drugs

You must not take recreational drugs if you are taking Tadalafil. Doing so can cause be very dangerous.

Pregnancy and breastfeeding

This drug should not be used by women.


The leaflet advises that while a reduction in sperm was noted in some men in testing, this is not likely to lead to infertility.

Driving and using machinery

If you feel dizzy or tired after taking this medication, do not drive or use machines.

Lactose intolerance

Tadalafil pills contain lactose. Tell your prescriber if you are lactose intolerant.


Can I still drink alcohol?

Drinking alcohol can exacerbate ED, and doing so while using Tadalafil tablets may increase the risk of ‘postural hypotension’. You should limit your alcohol consumption if you are using this treatment.

Will I still be able to drive?

Yes, provided you experience no side effects which affect your ability to do so. If you do, avoid driving and tell your doctor as soon as possible.

How do I store it?

In a safe place, out of the reach of children and at room temperature.

Am I allergic to anything in the medicine?

This drug contains: tadalafil, lactose monohydrate, croscarmellose, hydroxypropyl cellulose, sodium laurilsulphate, microcrystalline cellulose, magnesium stearate, opadry yellow, hypromellose, titanium dioxide (E171), triacetin, talc, iron oxide yellow (E172), or iron oxide red (E172).
Do not use it if you allergic to any of these ingredients.

Is it available over-the-counter?

No. You must have a prescription in order to buy Tadalafil.

Is it right for me?

If you have not used Tadalafil tablets before, talk to your GP to find out more about this drug and whether it can help you.
If you are looking to renew your Tadalafil prescription, take our consultation today. It takes just a few minutes and your answers will be reviewed by a GMC-registered physician or a UK pharmacy prescriber. Once your order has been confirmed as suitable, our CQC-approved pharmacy will dispense and ship your treatment by secure next-day delivery.